Search results for " Thyroid gland"

showing 8 items of 8 documents

Iatrogenic hypoparathyroidism after surgery for retrosternal goitre. A single centre retrospective analysis

2018

AIM: The aim of this study is to assess, retrospectively, the incidence of secondary hypoparathyroidism after total thyroidectomy in patients with retrosternal goitre. MATERIAL AND METHODS: From January 2009 to September 2015, 622 patients who undergone total thyroidectomy for goitre, were retrospectively observed. The patients were divided into two group: Group A, including 58 patients with retrosternal goitre and Group B, including 562 patients with in situ goitre. Those patients with diseases of the parathyroid glands, assumption of drugs modifying calcium metabolism and who received blood transfusions before or after surgery, were excluded from the study. In both groups, a total thyroid…

AdultMaleGoitreThyroid glandHypocalcemiaGoiterHypoparathyroidismRetrosternal goitreIncidenceIatrogenic DiseaseHypocalcaemiaSettore MED/21 - Chirurgia ToracicaLength of StayMiddle AgedSettore MED/18 - Chirurgia GeneraleThyroidectomyHumansCalciumFemaleGoitre; Hypocalcaemia; Hypoparathyroidism; Retrosternal goitre; Thyroid gland; ThyroidectomyAgedRetrospective Studies
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Skull-Cervico-Mandibular Unit: Correlation between Hyoid Bone, Thyroid Gland and Posture

2010

Purpose: The aim of this study is to evaluate the postural control of the patient with pathology or surgery of the neck area. We have examined a group of subjects with thyroid pathology and destined to total thyroidectomy. Method: Our sample comprised 10 patients (7 female and 3 male; mean age 50,9±15,8). They have been submitted to postural examination, before and after total thyroidectomy, using the baropodometric platform, the scoliosismeter and the ocular convergence test. All the values obtained from the baropodometric tests executed before and after thyroidectomy have been compared using a statistical analysis. The T Student test and a significant level of 5% (a=0,05;p£,05) have been …

Settore MED/28 - Malattie Odontostomatologicheposture postural examination thyroid gland hyoid bone.
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Tumorigenic and metastatic activity of human thyroid cancer stem cells

2010

Abstract Thyroid carcinoma is the most common endocrine malignancy and the first cause of death among endocrine cancers. We show that the tumorigenic capacity in thyroid cancer is confined in a small subpopulation of stem-like cells with high aldehyde dehydrogenase (ALDHhigh) activity and unlimited replication potential. ALDHhigh cells can be expanded indefinitely in vitro as tumor spheres, which retain the tumorigenic potential upon delivery in immunocompromised mice. Orthotopic injection of minute numbers of thyroid cancer stem cells recapitulates the behavior of the parental tumor, including the aggressive metastatic features of undifferentiated thyroid carcinomas, which are sustained by…

OncologyMaleCancer ResearchLung NeoplasmsPapillaryNudeMessengerThyroid GlandFluorescent Antibody TechniqueTYROSINE KINASEMice SCIDCell TransformationImmunoenzyme TechniquesMiceMice Inbred NODCell MovementAdenocarcinoma FollicularThyroid cancerRADIOACTIVE IODINETumor Stem Cell AssayEPITHELIAL-MESENCHYMAL TRANSITION; ALDEHYDE DEHYDROGENASE-ACTIVITY; ACUTE MYELOID-LEUKEMIA; RADIOACTIVE IODINE; TYROSINE KINASE; LUNG-CANCER; CARCINOMA; RECEPTOR; GROWTH; DIFFERENTIATIONBlottingReverse Transcriptase Polymerase Chain ReactionThyroidMiddle AgedProto-Oncogene Proteins c-metFlow CytometryEPITHELIAL-MESENCHYMAL TRANSITIONmedicine.anatomical_structureCell Transformation NeoplasticDIFFERENTIATIONOncologyNeoplastic Stem CellsAdenocarcinomaGROWTHFemaleStem cellWesternAdultmedicine.medical_specialtyBlotting WesternMice NudeACUTE MYELOID-LEUKEMIABiologyAdenocarcinomaSCIDALDEHYDE DEHYDROGENASE-ACTIVITYThyroid carcinomaYoung AdultLUNG-CANCERAdenocarcinoma Follicular; Adult; Aged; Aldehyde Dehydrogenase; Animals; Blotting Western; Carcinoma; Carcinoma Papillary; Case-Control Studies; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Transformation Neoplastic; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Lung Neoplasms; Male; Mice; Mice Inbred NOD; Mice Nude; Mice SCID; Middle Aged; Neoplasm Invasiveness; Neoplastic Stem Cells; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; RNA Messenger; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Gland; Thyroid Neoplasms; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays; Young Adult; Cancer Research; OncologyCancer stem cellSettore MED/04 - PATOLOGIA GENERALEInternal medicinemedicineCell AdhesionAnimalsHumansNeoplasm InvasivenessRNA MessengerThyroid NeoplasmsALDH Human Thyroid Cancer Stem CellsAgedCell ProliferationNeoplasticRECEPTORCarcinomaFollicularTumor Stem Cell AssayCancerAldehyde Dehydrogenasemedicine.diseaseXenograft Model Antitumor AssaysCarcinoma PapillaryCase-Control StudiesInbred NODRNAProto-Oncogene Proteins c-akt
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Number and size of rat thyroid C cells: No effect of pinealectomy

1985

A method for the estimation of the size and total number of calcitonin-containing cells (C cells) in the rat thyroid gland has been devised. The total area, the number of C cells per unit area, and the areal fraction of C cells were determined for the C cell region using step serial sections. From these data it was estimated that from 0.3 X 10(6) to 1.0 X 10(6) C cells were evenly divided between the two thyroid lobes. Approximately 150 micron3 of cytoplasm were associated with each of these cells. In comparison with sham-operated rats, pinealectomy had little effect on the number of C cells. In an experiment terminated in the summer, there was a statistically insignificant decrease 6 weeks…

medicine.medical_specialtyParafollicular cellmedicine.medical_treatmentCellThyroidPinealectomyBiologyAgricultural and Biological Sciences (miscellaneous)Rat Thyroidmedicine.anatomical_structureEndocrinologyCytoplasmInternal medicinemedicineAnatomyRat Thyroid GlandCell regionThe Anatomical Record
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Primary schwannoma of the thyroid gland involving the isthmus: report of a case

2013

Primary thyroid schwannomas are extremely rare tumors and there are very few reports of such tumors in the literature. This report presents a rare case of schwannoma involving the isthmus of the thyroid in a 47-year-old male, presenting as a symptomatic predominating cold nodule within a multinodular goiter. The patient underwent total thyroidectomy. The histological examination indicated an Antoni A-type schwannoma. The clinical, radiological and pathological findings of the tumor are discussed, emphasizing the difficulty in reaching a correct preoperative diagnosis. Only 18 cases of primary schwannoma of the thyroid gland have so far been described in the literature and, this is only the …

Maleendocrine systemPathologymedicine.medical_specialtyendocrine system diseasesmedicine.medical_treatmentThyroid GlandSchwannoma Thyroid glandSettore MED/08 - Anatomia PatologicaSchwannomaSurgical oncologyotorhinolaryngologic diseasesmedicineHumansThyroid NeoplasmsCold nodulePathologicalHistological examinationTotal thyroidectomybusiness.industryThyroidThyroidectomyGeneral MedicineMiddle Agedmedicine.diseasenervous system diseasesSettore MED/18 - Chirurgia GeneraleTreatment Outcomemedicine.anatomical_structureThyroidectomySurgerybusinessNeurilemmomaSurgery Today
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The THYCOVIT (Thyroid Surgery during COVID-19 pandemic in Italy) study: results from a nationwide, multicentric, case-controlled study

2021

AbstractThe outbreak of the COVID-19 pandemic has led to a disruption of surgical care. The aim of this multi-centric, retrospective study was to evaluate the impact of the pandemic on surgical activity for thyroid disease among the Italian Units of Endocrine Surgery. Three phases of the pandemic were identified based on the epidemiological situation and the public measures adopted from the Italian Government (1st phase: from 9th March to 3rd May 2020; 2nd phase: from 4th May to 14th June; 3rd phase: from 15th June to 31st). The patients operated upon during these phases were compared to those who underwent surgery during the same period of the previous year. Overall, 3892 patients from 28 …

COVID-19; Endocrine surgery; SARS-CoV-2; Thyroid carcinoma; Thyroidectomymedicine.medical_specialtymedicine.medical_treatmentThyroid GlandCOVID-19; Endocrine surgery; SARS-CoV-2; Thyroid carcinoma; Thyroidectomy; Humans; Italy; Retrospective Studies; SARS-CoV-2; COVID-19; Pandemics; Thyroid GlandNOThyroid carcinomaRetrospective StudiePandemicEpidemiologymedicineHumansThyroid cancerPandemicsLS7_4Retrospective StudiesPandemicbusiness.industrySARS-CoV-2Thyroid diseaseThyroidectomyCase-control studyCOVID-19Retrospective cohort studymedicine.diseaseSurgeryEndocrine surgeryEndocrine surgeryItalyThyroidectomyOriginal ArticleSurgerybusinessHuman
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Mucocele of the dorsal surface of the tongue : a case report

2018

Mucoceles represent one of the most common lesions of the oral cavity, developing as a result of saliva accumulation. The most frequent affected area is the lower lip, followed by floor of mouth, ventral tongue and buccal mucosa. Despite numerous reports of mucoceles originating on the ventral surface of the tongue, only scarce cases of such a lesion identified on the dorsal tongue surface have been described. In this report a mucocele developed on the dorsal tongue of a 74-year-old woman is described. Additionally a review of previously published mucoceles of the dorsal surface of the tongue is provided and discussed. A 74-year-old female patient was referred for a painless swelling on the…

DorsumGranular cell tumorOral Medicine and Pathologymedicine.diagnostic_testbusiness.industryConnective tissueCase Report030206 dentistryAnatomyLingual Thyroid Glandmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Lesion03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureTongue030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASBiopsymedicineMucocelemedicine.symptombusinessGeneral Dentistry
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Growth hormone potentiates thyroid hormone effects on post-exercise phosphocreatine recovery in skeletal muscle.

2012

International audience; OBJECTIVE: The aim of the study was to determine the respective impact of thyroxine and growth hormone on in vivo skeletal mitochondrial function assessed via post exercise phosphocreatine recovery. DESIGN: The hind leg muscles of 32 hypophysectomized rats were investigated using (31)P nuclear magnetic resonance spectroscopy at rest and during the recovery period following a non tetanic stimulation of the sciatic nerve. Each rat was supplemented with hydrocortisone and was randomly assigned to one of the 4 groups: the group Hx was maintained in hypopituitarism., the group HxT was treated with 1 μg/100g/day of thyroxine (T4), the group HxG with 0.2 IU/kg/day of recomb…

MalePhosphocreatineThyroid hormonesEndocrinology Diabetes and MetabolismMESH: Random AllocationThyroid GlandSkeletal muscleHypopituitarismMESH: Physical Conditioning AnimalMESH: Drug SynergismNuclear magnetic resonancechemistry.chemical_compoundRandom Allocation0302 clinical medicineEndocrinologyMESH: Human Growth HormoneMESH: AnimalsMESH : Muscle Skeletal0303 health sciencesMESH: Muscle Skeletal[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingMESH : RatsHuman Growth HormoneThyroidDrug Synergismmedicine.anatomical_structuremedicine.drugmedicine.medical_specialtyMESH : Drug SynergismMESH: RatsMESH : MaleSomatotropin030209 endocrinology & metabolismMESH: PhosphocreatinePhosphocreatineMESH : Random Allocation03 medical and health sciencesIn vivoInternal medicine[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyPhysical Conditioning AnimalMESH : Thyroxinemedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingAnimalsHumansMESH : PhosphocreatineMESH : Human Growth HormoneMitochondrionMESH : Physical Conditioning AnimalMuscle Skeletal030304 developmental biologyHydrocortisoneMESH: HumansMESH : HumansSkeletal muscleMESH : Thyroid GlandMESH: Thyroxinemedicine.diseaseMESH: MaleMESH: Thyroid GlandRatsThyroxineEndocrinologychemistryRatMESH : AnimalsTetanic stimulation[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyHormoneGrowth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
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